» "My Drug Dealers Name Is Bob... True Story."

» "Now The Clothes Are Always Dirty, The Dishes Are Never Clean, The Dogs Have Fleas And I Think The Fish Are Dead..."

» "I Would Kill The Clone, That Would Be My First Response."

» "I have two cats, four fish, and we used to have a mouse named Fluffball, but he just died. We gave him a proper burial in the backyard, and everyone said something nice about him."

» "If you're middle aged... where're you going to go to meet someone? You're not going to go to a bar,you're not going to go to a night club; and there are the museums."

» "It doesn't happen very often that you get to work with some really good friends of yours and there's a common language between everyone, you don't have to explain what you're doing, you can just run with it. It makes it just so much easier and more relaxed."

» "It seems like all the good looking people have smaller dogs these days. Especially for the women, because they always come in with their little Chihuahuas and the guys come in with their Golden Retrievers."

» "My oldest step-son wants to direct or produce. As far as being an actor, I've already told them they have to wait until they're 18; I won't take them to auditions."

» "My sisters are very academically inclined so whenever they would fix me up , it would always be from someone in their world, people they would find attractive. When they came to the door in suits, it was over."

» "Right now, my daughter's just rolling her eyes at everything I do; I'm just an embarrassment."

» "We're animal people."

» "I used to hop trains, smoke marijuana in the bathroom, steal English muffins from the dining hall..."

» "We were in the third day of final exams and strung out of coffee and cigarettes"

» "I love smoking. I quit when I was pregnant but it really relaxes me."

» "Those blue jeans looked great, you know? I mean the boy looks good. It was such a drag working with Jon Bon Jovi, the rock star, every day. It was so difficult just to walk out on the set."

» "I'm doing a series on Showtime called Weeds, which is about marijuana, so I'm going to be the marijuana mom at school now."

» (about blind dating): "I'd definitely consider it. My friend from high school went to internet dating and found a guy and they've been together for six years."

» "I refuse to go out with a man whose ass is smaller than mine."

» "Diane Lane and I have been really good friends for about 12 years now, so we usually spent every lunch together and after work and before work.".

» "My nickname among my group of friends is 'Mother,' and I tend to take care of everybody."

» "You don't necessarily always want to be with someone who works in your business. It takes a certain kind of couple that are both actors to be able to make it, and it takes a certain kind of ego and lack of competition and ability to really sustain a relationship while you're spending a lot of time apart. I'm with a cinematographer. He's very stable, and I'm highly neurotic - so it works."

» "I'm taking smaller roles than I would have 10 or 15 years ago. It's just the nature of aging in Hollywood. It's always harder for women."

» "I've never posed nude before, and I figured this would be the last time anyone would ask," Perkins joked with USA TODAY. "It's nice to see a middle-aged woman being viewed sexually. I want to celebrate all kinds of women, not just 20-year-olds."

»“You don’t necessarily always want to be with someone who works in your business. It takes a certain kind of couple that are both actors to be able to make it, and it takes a certain kind of ego and lack of competition and ability to really sustain a relationship while you’re spending a lot of time apart. I'm with a cinematographer. He’s very stable, and I’m highly neurotic - so it works.”

"There are actors who live behind gated houses and only hang out with other famous people. They go to parties and openings and premieres, and that's what they do. And then they get a part as a blue-collar worker and they just look like an idiot, because they don't understand real life. They don't ever see it."

"I'm not attracted to anything that's not off the beaten path, I get very bored playing comfortable people, people that just kind of come in and out of the room. I'd much prefer stumbling over the ottoman like Dick Van Dyke. That's the way I'd like to make an entrance. Just strolling into the room is not something I'm attracted to."

"I don't give a shit about that stuff. You'll never see me at the opening of something unless I'm in it. I won't go to an awards ceremony unless I'm nominated. I find the spotlight the most painful part of life in Hollywood. I'm not remotely interested in fame."

"A few people have heard that I was very demanding in terms of what I want, so I've become 'hard to work with.' But that's really unfair. All you're doing is trying to put in your creative input so you're not just flouncing around like some bimbo. It's very frustrating because I'm not a robot. You don't turn me on and I do my little job, and you shut me off and put me in my trailer. That's not the way I operate. If that's the kind of actress you want, then you shouldn't cast me."

"Though at home I'm the alcoholic pill-popper, I'm bound and determined to clean up Agrestic and make it a drug-free zone, I'm sorta the voice of the American government right now." (On Celia)

"This country hates marijuana and it's always going to be that way. [But] we're trying to get rid of all the cigarettes. What about all the cigarette factories? They're just missing this huge tax opportunity. Why not just change the cigarette factories to marijuana factories and everybody'll make a lot of money?"

"The minute you see people walking down the street, or you see women with strollers and they're walking their dogs you tend to think 'god their life is perfect, and mine is so fucked up' and yet the reality is that we're all kinda fucked up it's just that on the outside we all look kinda perfect."

"Celia is damaged, She thinks she's never really lived the life she feels she deserves. She's the most politically incorrect person in town and at home she is a nightmare. Her husband is screwing the tennis pro and she can't divorce him because that would mean giving up her lifestyle. Her daughter is fat and she can't see beyond that. It is a pleasure to play someone so unheroic."

"I'm more grateful that at this point in my life I'm 45, I'm still working and I've been given a great role. I'm extremely grateful to be going to work every day, I haven't felt that way for years."

"My life consists of a lot of driving, a lot of opening the wallet, a lot of laundry. We also have two dogs, two cats and fish. We live in a big house that is never clean. It's crazy and it's family."

"Celia just seemed tailor-made for my kind of humor. I never know what fucked-up thing I'm gonna be doing next week.''

"I'm not beautiful in today's hollywood. I'm not blonde, I'm not svelte. I don't have the long wavy hair, and sex isn't what I use to sell my characters. Instead I'm strong, I'm forceful and I'm pretty smart."

"Reading about it doesn't bother me at all, but I hate the sight of blood."

"I don't care what anybody says. No matter how successful you are, no matter how beautiful, being insecure is a fact of life, especially for women."

"I'm a complete slob."

"Susan ('Big') is the closest I've ever played to myself, she's this very motivated businesswoman who still has a little girl trapped inside of her, trying to get out."

"I couldn't understand why you had to go to class at a specific time, so I didn't."

"I've been dramatic from the day I was born"

"I don't think of myself as some tragic artist. But I am easily punctured."

"I mean, a crane could fall behind Jeff Daniels, and he wouldn't look up from his sports novel. You could throw a piece of dog shit at Tom Hanks in the middle of a scene, and it wouldn't faze him. For me, it would depend on who was throwing the dogshit."

"I did drugs until I was sick of them; I drank until I was sick of that; I fought and argued till I was sick of that; I'll stop smoking when I'm sick of that."

"I have weird taste"

''Every time we go out there (the suburbs), we're like, We can do this, and then we're there for a couple of hours, and it's like, You have to get me out of here. I'd become an alcoholic.''

"It never occurred to me that I was a diamond-getting kind of gal"

''I've worked consistently for 20 years and I've been able to fly below the radar and make a terrific living for my kids"

"I always thought that when I got to be around 40, I'd develop sophisticated taste in clothes, or that my purse would suddenly be clean. But I think I'm always going to have something like... a Barbie doll's head in my purse."

''I'm gonna be 45 in November, and I'm not lying, And I've had no plastic surgery!''

"I buy too many scented candles and perfumes. I like to spray my furniture with perfume so I can sit on it and absorb."

"I said to my husband, 'They just asked me to pose nude for Allure.' He said, 'You're gonna do it right?' And my daughter goes, 'If you do it, I'll kill you.' So I decided right there that I had to do it."

"If I were to have them choose, I'd rather they have a puff of a joint than a fifth of vodka."

''I had a very drunk guy come up to me once in New Orleans and say, 'Do you know who you are?' And I said something like, 'Do you know who you are? Does anyone know who they are?''

"I've never posed nude before, and I figured this would be the last time anyone would ask, It's nice to see a middle-aged woman being viewed sexually. I want to celebrate all kinds of women, not just 20-year-olds."

"Oh Yeah, I've Got Many Vices, And I'm Not Gonna Admit Any Of Them, But Yeah I've Got Plenty."

"Personally, I'm Not Sure Why Marijuana's Not Legalized."

"My Drug Dealers Name Is Bob... True Story."

"Now The Clothes Are Always Dirty, The Dishes Are Never Clean, The Dogs Have Mange, The Cats Have Fleas, All The Fish Are Dead..."

"I Would Kill The Clone, That Would Be My First Response."

"I have two cats, four fish, and we used to have a mouse named Fluffball, but he just died. We gave him a proper burial in the backyard, and everyone said something nice about him."

"If you're middle aged... where're you going to go to meet someone? You're not going to go to a bar,you're not going to go to a night club; and there are the museums."

"It doesn't happen very often that you get to work with some really good friends of yours and there's a common language between everyone, you don't have to explain what you're doing, you can just run with it. It makes it just so much easier and more relaxed."

"It seems like all the good looking people have smaller dogs these days. Especially for the women, because they always come in with their little Chihuahuas and the guys come in with their Golden Retrievers."

"My oldest step-son wants to direct or produce. As far as being an actor, I've already told them they have to wait until they're 18; I won't take them to auditions."

"My sisters are very academically inclined so whenever they would fix me up , it would always be from someone in their world, people they would find attractive. When they came to the door in suits, it was over."

"Right now, my daughter's just rolling her eyes at everything I do; I'm just an embarrassment."

"We're animal people."

"My nickname among my group of friends is 'Mother,' and I tend to take care of everybody."

"You don't necessarily always want to be with someone who works in your business. It takes a certain kind of couple that are both actors to be able to make it, and it takes a certain kind of ego and lack of competition and ability to really sustain a relationship while you're spending a lot of time apart. I'm with a cinematographer. He's very stable, and I'm highly neurotic - so it works."

"I used to hop trains, smoke marijuana in the bathroom, steal English muffins from the dining hall..."

"We were in the third day of final exams and strung out of coffee and cigarettes"

"I love smoking. I quit when I was pregnant but it really relaxes me."

"Those blue jeans looked great, you know? I mean the boy looks good. It was such a drag working with Jon Bon Jovi, the rock star, every day. It was so difficult just to walk out on the set."